Born in The Hague, the artist—also known as Corneille de La Haye—established himself in Lyon, France, by 1533. He became a prominent figure in the French courtly art scene, serving as a court painter to several French monarchs, including Catherine de' Medici.

His signature style is defined by miniature-like portraiture, typically executed in oil on small wooden panels. These works are characterized by their subtle modeling, precise detail, and neutral backgrounds, which focus the viewer's attention entirely on the subject's expression and features.

Today, his works are held in major museum collections worldwide, valued for their historical significance and technical refinement. He remains a key reference point for the study of Northern Renaissance portraiture and its influence on the French school of the 16th century.