Born in Prato, Italy, Filippino Lippi was the son of the painter Fra Filippo Lippi and the nun Lucrezia Buti. He received his early artistic training in his father's workshop before completing his apprenticeship under Sandro Botticelli, whose influence remained a defining element of his early aesthetic.

Lippi is celebrated for his mastery of tempera and oil, producing significant works such as the completion of the Brancacci Chapel frescoes in Florence and the decoration of the Carafa Chapel in Rome. His style is characterized by expressive, often elongated figures and a sophisticated use of color and detail that evolved throughout his career.

His legacy is cemented by his extensive contributions to the artistic landscape of 15th-century Italy, particularly in Florence and Rome. His works continue to be studied for their technical precision and their role in the stylistic development of the Italian Renaissance.