Born around 1430, Lieven van Lathem was an influential figure in the Early Netherlandish tradition. He was active primarily in the Southern Netherlands, where he established a reputation as a skilled manuscript illuminator and painter during the mid-to-late 15th century.

His work is characterized by the intricate detail and stylistic refinement typical of the period's manuscript production. He is recognized for his role in the artistic circles of the Burgundian court, contributing to the visual culture of the era through his commissions for high-profile patrons.