Born Marjorie Jewel Moss in London, she studied at the Slade School of Fine Art before moving to Paris in 1927. It was in France that she adopted the name Marlow and became deeply involved in the avant-garde circles of the time, eventually becoming a student and associate of Piet Mondrian.

Her work is characterized by a strict adherence to geometric principles, utilizing a limited palette and precise linear structures in both painting and relief sculpture. She was a founding member of the Abstraction-Création group, contributing significantly to the development of non-objective art in Europe during the 1930s.

Moss's historical importance continues to be recognized in major institutional surveys of early twentieth-century modernism. Her work is currently featured in the Stedelijk Museum's permanent collection presentation, Yesterday Today, which contextualizes her contributions alongside other key figures of the De Stijl and Bauhaus movements.