Born in New York City, Mira Schor is the daughter of artists Ilya and Resia Schor. She pursued her formal education at New York University and the California Institute of the Arts, where she studied under John Baldessari. Her career has been defined by a dual focus on studio practice and critical writing, establishing her as a significant voice in the discourse surrounding the relevance of painting.

Schor is known for her work that integrates text and image, often exploring themes of language, gender, and the history of art. Her practice frequently utilizes painting as a medium to interrogate the boundaries between personal narrative and broader cultural critique. She is also widely recognized for her editorial work, including her role as a co-founder of the journal M/E/A/N/I/N/G.

Her work has been exhibited in numerous institutions, and she remains an influential figure in feminist art criticism. Her writings, including her books on the state of contemporary painting, continue to be cited as essential texts for understanding the intersection of art practice and theoretical inquiry.