Born in New York City, Roni Horn developed a practice deeply rooted in the relationship between the viewer and the environment. Her early work often involved extensive travel, particularly to Iceland, which became a foundational influence on her conceptual approach to geography and perception.

Horn is widely known for her minimalist sculptures, often utilizing cast glass or metal, alongside expansive photographic series that examine subtle shifts in light, water, and human features. Her work frequently employs seriality to challenge the viewer's ability to perceive change over time.

Her work continues to be featured in major international exhibitions and institutional collections. Recent initiatives, including the inclusion of her monographs in collaborative reading room projects in Shanghai, highlight her ongoing presence in global contemporary art discourse.