Born in Oxford, England, Christina Mackie studied at the Vancouver School of Art and later at Saint Martin's School of Art in London. Her practice is defined by a rigorous engagement with the physical properties of materials and the ways in which they interact with architectural and social spaces.

Her work often manifests as large-scale, site-specific installations that combine found objects, industrial materials, and digital media. By juxtaposing disparate elements, she creates environments that invite viewers to consider the interconnectedness of natural systems and human-made structures.

Mackie continues to be a significant figure in the contemporary art scene, frequently exhibiting in major international institutions. Her work is noted for its intellectual depth and its ability to transform gallery spaces into immersive, thought-provoking landscapes.