Born Simbiatu Abisola Abiola Ajikawo in London, Little Simz began her career as an independent artist, releasing a series of mixtapes and EPs before her debut studio album, A Curious Tale of Trials + Persons, in 2015. Her early work established her as a formidable presence in the UK music scene, characterized by a distinct narrative style and technical proficiency.

Her signature sound blends elements of hip-hop, jazz, and soul, often exploring themes of identity, personal growth, and the complexities of modern life. Her 2019 album Grey Area served as a major breakthrough, earning her significant critical praise and multiple industry accolades, including an Ivor Novello Award for Best Album.

In recent years, her influence has extended beyond the recording studio into the cultural sphere. She is featured in the V&A East Museum's inaugural exhibition, The Music is Black: A British Story, which highlights her role in the evolution of contemporary British music over the past century.